U2 716 then LS 1787 at Manchester
Castletown → Manchester → Valletta
Timetable, Manchester time
09:25U2 716 from Castletown at the gate
06:15LS 1787 to Valletta leaves the gate
20 h 50 apart on the timetable, overnight
LS 1787 leaves 20 h 50 after U2 716 arrives on the timetable: more than half a day, so not a connection we count.