3S 440 then K4 221 at O'Hare
Frankfurt am Main → Chicago → Cincinnati Northern Kentucky
Timetable, Chicago time
18:123S 440 from Frankfurt am Main at the gate
16:20K4 221 to Cincinnati Northern Kentucky leaves the gate
22 h 08 apart on the timetable, overnight
K4 221 leaves 22 h 08 after 3S 440 arrives on the timetable: more than half a day, so not a connection we count.