AA 4454 then AA 4251 at O'Hare
Indianapolis → Chicago → Sioux Falls
Timetable, Chicago time
06:00AA 4454 from Indianapolis at the gate
22:48AA 4251 to Sioux Falls leaves the gate
16 h 48 apart on the timetable
AA 4251 leaves 16 h 48 after AA 4454 arrives on the timetable: more than half a day, so not a connection we count.