AA 6465 then 5X 5603 at O'Hare
Detroit → Chicago → Louisville
Timetable, Chicago time
07:40AA 6465 from Detroit at the gate
07:305X 5603 to Louisville leaves the gate
23 h 50 apart on the timetable, overnight
5X 5603 leaves 23 h 50 after AA 6465 arrives on the timetable: more than half a day, so not a connection we count.