AA 6486 then AA 4229 at O'Hare
Detroit → Chicago → Knoxville
Timetable, Chicago time
17:29AA 6486 from Detroit at the gate
13:45AA 4229 to Knoxville leaves the gate
20 h 16 apart on the timetable, overnight
AA 4229 leaves 20 h 16 after AA 6486 arrives on the timetable: more than half a day, so not a connection we count.