AA 6486 then AA 4498 at O'Hare
Detroit → Chicago → Harrisburg
Timetable, Chicago time
17:29AA 6486 from Detroit at the gate
11:45AA 4498 to Harrisburg leaves the gate
18 h 16 apart on the timetable, overnight
AA 4498 leaves 18 h 16 after AA 6486 arrives on the timetable: more than half a day, so not a connection we count.