AA 6486 then UA 1491 at O'Hare
Detroit → Chicago → Charleston (South Carolina)
Timetable, Chicago time
17:29AA 6486 from Detroit at the gate
10:40UA 1491 to Charleston (South Carolina) leaves the gate
17 h 11 apart on the timetable, overnight
UA 1491 leaves 17 h 11 after AA 6486 arrives on the timetable: more than half a day, so not a connection we count.