AA 6486 then UA 4382 at O'Hare
Detroit → Chicago → Buffalo
Timetable, Chicago time
17:29AA 6486 from Detroit at the gate
10:30UA 4382 to Buffalo leaves the gate
17 h 01 apart on the timetable, overnight
UA 4382 leaves 17 h 01 after AA 6486 arrives on the timetable: more than half a day, so not a connection we count.