AA 6486 then UA 4448 at O'Hare
Detroit → Chicago → Roanoke
Timetable, Chicago time
17:29AA 6486 from Detroit at the gate
14:10UA 4448 to Roanoke leaves the gate
20 h 41 apart on the timetable, overnight
UA 4448 leaves 20 h 41 after AA 6486 arrives on the timetable: more than half a day, so not a connection we count.