AA 6486 then UA 4601 at O'Hare
Detroit → Chicago → Columbia Regional
Timetable, Chicago time
17:29AA 6486 from Detroit at the gate
12:45UA 4601 to Columbia Regional leaves the gate
19 h 16 apart on the timetable, overnight
UA 4601 leaves 19 h 16 after AA 6486 arrives on the timetable: more than half a day, so not a connection we count.