AA 6486 then UA 5282 at O'Hare
Detroit → Chicago → Lexington
Timetable, Chicago time
17:29AA 6486 from Detroit at the gate
14:50UA 5282 to Lexington leaves the gate
21 h 21 apart on the timetable, overnight
UA 5282 leaves 21 h 21 after AA 6486 arrives on the timetable: more than half a day, so not a connection we count.