BR 646 then UA 4448 at O'Hare
Anchorage → Chicago → Roanoke
Timetable, Chicago time
17:10BR 646 from Anchorage at the gate
14:10UA 4448 to Roanoke leaves the gate
21 h apart on the timetable, overnight
UA 4448 leaves 21 h after BR 646 arrives on the timetable: more than half a day, so not a connection we count.