OO 6105 then AA 5580 at O'Hare
Lewisburg → Chicago → Knoxville
Timetable, Chicago time
12:37OO 6105 from Lewisburg at the gate
08:12AA 5580 to Knoxville leaves the gate
19 h 35 apart on the timetable, overnight
AA 5580 leaves 19 h 35 after OO 6105 arrives on the timetable: more than half a day, so not a connection we count.