AA 5789 then AA 1597 at Philadelphia
Manchester → Philadelphia → Charleston (South Carolina)
Timetable, Philadelphia time
09:00AA 5789 from Manchester at the gate
21:49AA 1597 to Charleston (South Carolina) leaves the gate
12 h 49 apart on the timetable
AA 1597 leaves 12 h 49 after AA 5789 arrives on the timetable: more than half a day, so not a connection we count.