KM 490 then U2 2194 at Zurich
Valletta → Zurich → Manchester
Timetable, Zurich time
16:50KM 490 from Valletta at the gate
10:10U2 2194 to Manchester leaves the gate
17 h 20 apart on the timetable, overnight
U2 2194 leaves 17 h 20 after KM 490 arrives on the timetable: more than half a day, so not a connection we count.