UA 2278 then AA 538 at O'Hare
San Francisco → Chicago → Des Moines
Timetable, Chicago time
05:04UA 2278 from San Francisco at the gate
10:50AA 538 to Des Moines leaves the gate
5 h 46 apart on the timetable
The last days
UA 2278 and AA 538 weren’t both flown 15 min to 12 h apart in the last 21 days.
Statistics from past flights, not live flight information. Always check times and your connection with your airline, and don’t base travel or booking decisions on these numbers.